Active Ingredient (Generic Name):	Metronidazole
Indication:	Bacterial & Parasitic infections
Manufacturer:	Abbott
Packaging:	15 Tablets in 1 Strip
Strength:	400 MG
Delivery Time:	6 To 15 days
SKU:	Flagyl 400 Mg

Flagyl 400 mg is the brand name for Metronidazole 400 mg, an antibiotic and antiprotozoal medication. It is used to treat a variety of bacterial and parasitic infections. Flagyl 400 mg works by inhibiting the DNA synthesis of microorganisms, which prevents them from growing and multiplying, helping to clear infections.

Uses of Flagyl 400 mg:

Flagyl 400 mg is prescribed to treat several types of bacterial and parasitic infections, including:

1. Bacterial Infections:
   • Anaerobic bacterial infections: These include infections of the gastrointestinal tract, reproductive organs, skin, and respiratory system.
   • Intra-abdominal infections: Such as peritonitis or abscesses.
   • Dental infections: For example, abscesses or gum infections.
   • Skin and soft tissue infections caused by anaerobic bacteria.
2. Parasitic Infections:
   • Giardiasis: A parasitic infection of the small intestine caused by Giardia lamblia.
   • Amebiasis: An intestinal infection caused by Entamoeba histolytica.
   • Trichomoniasis: A sexually transmitted infection caused by Trichomonas vaginalis.
   • Amoebic liver abscess: Infection in the liver due to Entamoeba histolytica.
3. Pelvic Inflammatory Disease (PID): Often used in combination with other antibiotics to treat PID, which involves infection of the female reproductive organs.

How It Works:

Metronidazole (Flagyl 400 mg) works by entering bacterial or parasitic cells and interfering with their DNA, which prevents them from reproducing. This halts the growth of bacteria and parasites, ultimately leading to their death and the resolution of the infection.

Dosage:

• For adults: The usual dose for Flagyl 400 mg is 400 mg every 8 to 12 hours for bacterial infections, typically for 5 to 10 days, depending on the type and severity of the infection.
• For parasitic infections: The dosage may vary depending on the infection being treated (e.g., giardiasis, trichomoniasis). The treatment duration may range from 1 day to several weeks.
• For children: The dosage is based on the child’s age, weight, and type of infection. Always follow your doctor’s instructions for dosing.

Side Effects:

Common side effects of Flagyl 400 mg include:

• Nausea or vomiting
• Diarrhea
• Metallic taste in the mouth
• Headache
• Dizziness or light-headedness
• Stomach pain
• Rash
• Dry mouth

Serious Side Effects:

While rare, some serious side effects can occur with Flagyl 400 mg:

• Severe allergic reactions (e.g., rash, swelling of the face or throat, difficulty breathing)
• Liver problems (e.g., yellowing of the skin or eyes)
• Severe neurological reactions (e.g., seizures, numbness, or tingling in the hands or feet)
• Severe diarrhea (Clostridium difficile-associated diarrhea)
• Dark or reddish urine (this may be temporary but should be reported to a doctor)

Precautions:

• Allergy: Avoid using Flagyl if you are allergic to metronidazole or other nitroimidazole antibiotics.
• Liver disease: If you have liver problems, your doctor may need to adjust your dose or monitor liver function during treatment.
• Pregnancy: Flagyl 400 mg is classified as Category B for pregnancy (no evidence of harm in animal studies, but human studies are limited). It should only be used during pregnancy if necessary and prescribed by a doctor.
• Breastfeeding: Metronidazole passes into breast milk, so consult your doctor before breastfeeding while on this medication.
• Alcohol: Avoid alcohol consumption while taking Flagyl and for at least 48 hours after the last dose. Alcohol can cause severe reactions, such as nausea, vomiting, and headache.

1. What is Flagyl 400 mg used for?

Flagyl 400 mg is an antibiotic used to treat various bacterial and parasitic infections, including:

• Bacterial infections like intra-abdominal infections, dental infections, and pelvic inflammatory disease (PID).
• Parasitic infections like giardiasis, amebiasis, and trichomoniasis.
• Skin infections and vaginitis caused by anaerobic bacteria.
• H. pylori eradication in peptic ulcers.

2. How does Flagyl 400 mg work?

Flagyl 400 mg (Metronidazole) works by disrupting the DNA structure of bacteria and parasites, preventing them from growing and multiplying. This ultimately helps clear the infection.

3. How should I take Flagyl 400 mg?

Flagyl 400 mg is typically taken orally as a tablet. The usual dosage is one tablet every 8 to 12 hours for a prescribed number of days, depending on the infection. It is recommended to take it with food to minimize stomach upset.

4. What if I miss a dose of Flagyl 400 mg?

If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take two doses at once to make up for a missed dose.

5. Can I stop taking Flagyl 400 mg when I feel better?

No, you should complete the full course of Flagyl 400 mg, even if you feel better before finishing the medication. Stopping the treatment early can lead to the infection returning or the development of antibiotic resistance.